Only a Priest of Magranon can cast this spell
Can be cast on both aggressive and non-aggressive creatures.
Will take the target down to very low health (typically "dying" status), but never kill it, with damage based on cast power.
It's suspected to have the same effect as the Orb of doom, but where the artifact is a weapon of mass destruction, Smite only affects the target of the spell.
Offensive spell resistance
Many offensive spells in the game now also have their own resistances. These function identically to the healing resistance above, but have much lower maximum duration for their resistance values. The duration of this effect is based on how much damage is done, and will reduce all further damage on the target from the same spell.
The maximum duration of resistance various depending on the spell, and the reduction scales linearly from that mark. For example, if you have 1 minute of resistance remaining and the spell has a maximum resistance duration of 2 minutes, you will receive 50% normal damage from a further cast of that spell.
Smite has a maximum resistance duration of 5 minutes.