Can be cast on both aggressive and non-aggressive creatures.
Will take the target down to very low health (typically "dying" status), but never kill it, with damage based on cast power.
It's suspected to have the same effect as the Glass Orb of Doom, but where the artifact is a weapon of mass destruction, Smite only affects the target of the spell.
Offensive spell resistance
Many damaging spells and grant the targeted player a resistance effect. This duration of this effect is based on how much damage is done, and will reduce all further damage on the target from the same spell.
The maximum duration of resistance various depending on the spell, and the reduction scales linearly from that mark. For example, if you have 1 minute of resistance remaining and the spell has a maximum resistance duration of 2 minutes, you will receive 50% normal damage from a further cast of that spell.
Smite has a maximum resistance duration of 5 minutes.